Provides a unique overview of efficient synthetic routes to one of the most important compound
classes in organic and pharmaceutical chemistry! Amines are among the most important compounds
in organic chemistry due to their wide occurrence in natural products drugs crop protection
compounds and advanced materials. For example the majority of drugs are amines or contain
functional groups derived from amines. Powerful and efficient methods for the introduction of
the amino group are therefore of great importance to synthetic chemists in academia and
industry. Methodologies in Amine Synthesis ? Challenges and Applications presents powerful and
state-of-the-art methods for the efficient preparation of amines. It summarizes recent advances
in the electrophilic amination reaction hydroamination C?H amination as well as newly
developed photocatalytic approaches. It further describes organocatalytic and enzymatic routes
to the generation of amines under mild and environmentally friendly conditions. In addition it
highlights the relevance of the amino function in bioactive molecules drugs and in the
engineering of smart materials. Finally the application of palladium-catalyzed aromatic
amination in industrial context is critically discussed. * Only up-to-date and comprehensive
book on the preparation of amines ? one of the most frequently occurring compound classes found
in natural products bioactive molecules and advanced materials. * Presents efficient and
useful synthetic methods highlights opportunities challenges as well as applications in
pharmaceutical chemistry and materials science. * Chapters are compiled by well-known experts
in the field. One of them edited the previous books ?Modern Amination Methods? (2001) and
?Amino Group Chemistry? (2007). The book Methodologies in Amine Synthesis ? Challenges and
Applications is a musthave for chemists in academia and industry working in the field of
organic synthesis and catalysis natural product chemistry drug synthesis and pharmaceutical
chemistry as well as materials science.
