The book is unique in that it bridges the gap between bioinformaticists and molecular
biologists i.e. the developers and the users of computational methods for biological data
analysis and in that it presents examples of practical applications of the bioinformatics tools
in the daily practice of an experimental research scientist. The book starts with reviews on
computational methods for protein sequence-structure-function analysis (sequence studies
structure prediction) followed by methods that explicitly utilize experimental data routinely
obtained in the laboratory to improve the functional predictions. The second part comprises a
series of examples on how particular applications of different types of bioinformatics methods
in combination with experimental studies to validate the hypotheses have led to important
scientific discoveries. Therefore the book is a guide to application of bioinformatics methods
in molecular biology addressed mainly to researchscientists postdocs and advanced graduate
students.
