To make innovations work commercially among the target group requires institutional approach
that can anticipate and predict users' urgent needs through participation. Conversely to make
innovations work technically requires a pile of junk and good imagination according to Thomas
Edison. Biotechnology no doubt is a significant innovation that can enable farmers in
developing countries increase productivity and manage their products. Nevertheless biotech
application is surrounded with many controversial debates. These controversies have affected
its perception among farmers and consumers alike. Using a mixed method approach empirical data
were gathered from farmers and extension agents in six geopolitical divisions of Nigeria to
determine factors capable of ensuring sustainable biotech adoption. Results revealed that the
probability of biotech adoption is dependent on a cause and effect relationship.
