This book constitutes the refereed proceedings of the 13th Annual International Conference on
Research in Computational Molecular Biology RECOMB 2009 held in Tucson Arisona USA in May
2009.The 37 revised full papers presented were carefully reviewed and selected from 166
submissions. As the top conference in computational molecular biology RECOMB addresses all
current issues in algorithmic theoretical and experimental bioinformatics such as molecular
sequence analysis recognition of genes and regulatory elements molecular evolution protein
structure structural genomics gene expression gene networks drug design combinatorial
libraries computational proteomics as well as structural and functional genomics.