This book examines the means by which non-enveloped viruses penetrate cellular membranes during
cell entry. It will help elucidate the mechanisms of non-enveloped virus membrane penetration
in general. The means by which non-enveloped viruses penetrate cellular membranes during cell
entry remain poorly defined. Recent findings indicate several members of this group share a
common mechanism of membrane penetration in which the virus particle undergoes programmed
conformational changes leading to capsid disassembly and release of small membrane-interacting
peptides. A complete understanding of host cell entry by this minimal system will help
elucidate the mechanisms of non-enveloped virus membrane penetration in general
