Recent progress on enzyme immobilisation enzyme production coenzyme regeneration and enzyme
engineering has opened up fascinating new fields for the potential application of enzymes in a
large range of different areas. As more progress in research and application of enzymes has
been made the lack of an up-to-date overview of enzyme molecular properties has become more
apparent. Therefore we started the development of an enzyme data in formation system as part
of protein-design activities at GBF. The present book Enzyme Handbook represents the printed
version of this data bank. In future a computer searchable version will be also available. The
enzymes in this Handbook are arranged according to the Enzyme Commission list of enzymes. Some
3000 different enzymes will be covered. Frequently enzymes with very different properties are
included under the same EC number. Although we intend to give a representative overview on the
characteristics and variability of each enzyme the Handbook is not a com pendium. The reader
will have to go to the primary literature for more detailed information. Naturally it is not
possible to cover all the numerous literature references for each enzyme (for special enzymes
up to 40000) if the data re presentation is to be concise as is intended.