EAN: 9783863594763

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Focal segmental glomerulosclerosis (FSGS) is responsible in the majority of renal patients for
progression to end-stage renal disease (D'Agati VD et al. 2011). Considering that parietal and
visceral epithelial cells play important roles in the pathogenesis of rapidly progressive
glomerulonephritis (RPGN) and FSGS  the major aim of this work was to provide a highly
efficient and reliable approach for isolation and generation of a primary culture of parietal
epithelial cells and podocytes from two different transgenic mice.

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