This study applies extraction of hexane-1 6-diamine from a cell-containing aqueous
biotechnological production medium. Promising reactive extractants and solvents were
identified. A simulation was successfully validated in pilot-scale experiments. In addition
the column was used as bioreactor with integrated aeration and product extraction. The
feasibility of in-situ reactive extraction of hexane-1 6-diamine from cell containing
biotechnological production media was proven.