The present study was carried out for phytochemical screening and pharmacological
investigations on methanolic extract of rhizomes of Hedychium coronarium (Local name: Dolan
Champa Family: Zingiberaceae). In this study the possible analgesic and CNS (Central Nervous
System) depressant activities of the methanolic rhizome extract of Hedychium coronarium were
investigated at the doses of 100 mg Kg 200 mg kg and 400 mg Kg body weight on mice by oral
administration. The analgesic activities were investigated for their central and peripheral
pharmacological actions using tail immersion testing and acetic acid-induced writhing testing
respectively. Its CNS depressant activity was evaluated by using hole cross and open field
tests and the cytotoxic activity was observed using brine shrimp lethality bioassay.
