The book provides an intensive overview on exercise for cardiovascular disease prevention and
treatment from basic research to clinical practice. The volume firstly summarizes the acute
and chronic response to exercise. Secondly evidence for exercise as medicine for the heart
based on clinical studies and basic research is summarized. Thirdly molecular mechanisms
mediating the beneficial effects of exercise including IGF-1-PI3K-AKT signalling NO signalling
C EBPB-Cited4 signalling Non-coding RNAs epigenetic regulators mitochondria adaption and
exosomes are presented. Finally exercise dosing prescription and future prospects are
provided. This book will provide valuable reference for researchers in cell biology physiology
as well as physician physical therapist in cardiology sport medicine etc.