EAN: 9780896032767

COMPUTER ANALYSIS OF SEQUENCE DATA PART II - AN...

DNA sequencing has become increasingly efficient over the years  resulting in an enormous
increase in the amount of data gener ated. In recent years  the focus of sequencing has shifted
from being the endpoint of a project  to being a starting point. This is especially true for
such major initiatives as the human genome project  where vast tracts of DNA of unknown
function are sequenced. This sheer volume of available data makes advanced computer methods
essen tial to analysis  and a familiarity with computers and sequence analy sis software a
vital requirement for the researcher involved with DNA sequencing. Even for nonsequencers  a
familiarity with sequence analysis software can be important. For instance  gene sequences
already present in the databases can be extremely useful in the design of cloning and genetic
manipulation experiments. This two-part work on Computer Analysis of Sequence Data is designed
to be a practical aid to the researcher who uses computers for the acquisition  storage  or
analysis of nucleic acid (and or pro tein) sequences. Each chapter is written such that a
competent scien tist with basic computer literacy can carry out the procedure successfully at
the first attempt by simply following the detailed prac tical instructions that have been
described by the author. A Notes section  which is included at the end of each chapter 
provides advice on overcoming the common problems and pitfalls sometimes encoun tered by users
of the sequence analysis software.

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