The acclaimed landmark guide to internal medicine-updated to reflect the latest guidelines and
recommendations The Voice of Clinical Reason For more than seven decades Harrison's
Principles of Internal Medicine has provided healthcare professionals with the informational
foundation needed to provide optimal patient care. The world's leading authority on applied
pathophysiology and clinical medicine this trusted resource has covered countless advances and
developments across the full span of medicine. Fully updated the new 22 nd edition has been
modified extensively in its structure and content and offers a standardized format for each
disease chapter. The authors and editors have curated and synthesized the vast amount of
information that comprises general internal medicine and each of the major specialties into a
highly readable and informative resource. Harrison's is world-renowned as the most
authoritative source for: ¿ Descriptions of disease mechanisms and how the clinician can
apply that knowledge for the best patient care and optimal diagnosis and treatment of specific
diseases ¿ Clear concise schemas that facilitate the generation of differential diagnoses to
reason efficiently through complex real world clinical cases ¿ The physiologic and
epidemiologic basis of signs and symptoms which are covered through a wealth of unsurpassed
expert guidance and linked to the disease-specific chapters that follow ¿ Updated clinical
trial results and recommended guidelines ¿ Excellent and extensive visual support including
radiographs clinical photos schematics and high-quality drawings ¿ Coverage of both
therapeutic approaches and specific treatment regimens ¿ Practical clinical decision trees and
algorithms ¿ Organ- and system-specific sections with clinically relevant pathophysiology and
practical clinical advice on the approach to the patient strategies towards building a
differential diagnosis outstanding clinical algorithms and diagnostic schema a wealth of
clinical images and diagrams current clinical guidelines as well as general and specific
approaches to therapy This twenty-second edition features: ¿ Updated content that reflects
new approved therapeutics and new practice-changing guidelines and evidence summaries ¿ More
than 3 000 clinical pathological and radiographic photographs diagnostic and therapeutic
decision trees and clear schematics and diagrams describing pathophysiologic processes ¿
Numerous atlases featuring curated collections of important visual aspects of diagnosis and
management ¿ Brand new chapters including The Value of the Physical Examination in Modern
Medicine Physician Well-Being Exercise Intolerance Primary and Secondary Hemophagocytic
Lymphohistiocytosis Symptom Control in Patients with Cancer Principles of Immunization COVID
and Other Coronavirus Infections Desensitization Point-of-Care Ultrasound Placebo and Nocebo
Effects Bedside Examination Tests in the Patient with Low Back Pain and Antithrombotic
Therapy in Adult Patients
