EAN: 9781441900845

COMPUTER SIMULATION AND DATA ANALYSIS IN MOLECU...

This book provides an introduction  suitable for advanced undergraduates and beginning graduate
students  to two important aspects of molecular biology and biophysics: computer simulation and
data analysis. It introduces tools to enable readers to learn and use fundamental methods for
constructing quantitative models of biological mechanisms  both deterministic and with some
elements of randomness  including complex reaction equilibria and kinetics  population models 
and regulation of metabolism and development  to understand how concepts of probability can
help in explaining important features of DNA sequences  and to apply a useful set of
statistical methods to analysis of experimental data from spectroscopic  genomic  and proteomic
sources. These quantitative tools are implemented using the free  open source software program
R. R provides an excellent environment for general numerical and statistical computing and
graphics  with capabilities similar to Matlab®. Since R is increasingly used in bioinformatics
applications such as the BioConductor project  it can serve students as their basic
quantitative  statistical  and graphics tool as they develop their careers.

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