Tumor-Induced Immune Suppression - Prospects and Progress in Mechanisms and Therapeutic
Reversal presents a comprehensive overview of large number of different mechanisms of immune
dysfunction in cancer and therapeutic approaches to their correction. This includes the number
of novel mechanisms that has never before been discussed in previous monographs. The last
decades were characterized by substantial progress in the understanding of the role of the
immune system in tumor progression. Researchers have learned how to manipulate the immune
system to generate tumor specific immune response which raises high expectations for
immunotherapy to provide breakthroughs in cancer treatment. It is increasingly clear that
tumor-induced abnormalities in the immune system not only hampers natural tumor immune
surveillance but also limits the effect of cancer immunotherapy. Therefore it is critically
important to understand the mechanisms of tumor-induced immune suppression to make any progress
in the field and this monograph provides these important insights.
