This volume explores label-free biosensors advantageous in part because this technology
bypasses the need of labels reporters and cell engineering all of which are common to
labeled techniques but may introduce artifacts in assay results. Addressing several fundamental
and practical aspects as to how to implement label-free methods in the drug discovery process
this book covers a wide range of topics including binding kinetics determination fragment
screening antibody epitope mapping protein-protein interaction profiling and screening
receptor pathway deconvolution drug pharmacology profiling and screening target
identification drug toxicity assessment and physical phenotype profiling and diagnostics
based on various cellular processes such as cell adhesion migration invasion infection and
inflammation. As part of the Methods in Pharmacology and Toxicology series chapters aim to
provide key detail and implementation advice to aid with progress in the lab.Practical and
thorough Label-Free Biosensor Methods in Drug Discovery provides a new avenue for rapid access
to a focused collection of highly regarded contributions in the field.
