EAN: 9781493940271

ANALYTICAL TECHNIQUES IN THE PHARMACEUTICAL SCI...

The aim of this book is to present a range of analytical methods that can be used in
formulation design and development and focus on how these systems can be applied to understand
formulation components and the dosage form these build. To effectively design and exploit drug
delivery systems  the underlying characteristic of a dosage form must be understood--from the
characteristics of the individual formulation components  to how they act and interact within
the formulation  and finally  to how this formulation responds in different biological
environments. To achieve this  there is a wide range of analytical techniques that can be
adopted to understand and elucidate the mechanics of drug delivery and drug formulation. Such
methods include e.g. spectroscopic analysis  diffractometric analysis  thermal investigations 
surface analytical techniques  particle size analysis  rheological techniques  methods to
characterize drug stability and release  and biological analysis in appropriate cell and animal
models. Whilst each of these methods can encompass a full research area in their own right 
formulation scientists must be able to effectively apply these methods to the delivery system
they are considering. The information in this book is designed to support researchers in their
ability to fully characterize and analyze a range of delivery systems  using an appropriate
selection of analytical techniques. Due to its consideration of regulatory approval  this book
will also be suitable for industrial researchers both at early stage up to pre-clinical
research.

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