EAN: 9781493972067

DEVELOPMENTAL AND REPRODUCTIVE TOXICOLOGY GEBUNDEN

This meticulous volume covers metabolism and drug-drug interactions during pregnancy  critical
periods of developmental toxicology  in vivo and alternative methods to assess potential
developmental toxicity for drugs and chemicals  and effects of chemicals on testes and mammary
glands. Evaluation of developmental and reproductive toxicology endpoints is an integral part
of the safety assessment process for compounds with potential use in women of childbearing age
or females that might be exposed during pregnancy as well as men of reproductive potential. The
in vivo assessments included here are guideline-driven and are required for submissions for
product approval. Written for the Methods in Pharmacology and Toxicology series  this
collection includes the kind of detailed implementation advice necessary for success in the
lab. Authoritative and practical  Developmental and Reproductive Toxicology is an ideal
resource for researchers working in this vital field of study.

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