EAN: 9783030016340

CURRENT TRENDS IN IMMUNITY AND RESPIRATORY INFE...

The purpose of this book is to disseminate and deliberate on the latest knowledge concerning
immunity and its role in protection and fight against microorganism invasion. The articles
tackle both humoral and cellular immunity  and their interconnectivity. The former involves B
cells that recognize invading pathogens and create the antibody-mediated response  which when
memorized provides future immunity. The latter involves mostly T cells  exemplified by
cytotoxic or killer cell destroying the pathogens  or helper cells stimulating B cells to
produce antibodies to bind and neutralize the pathogens. T cells act through release of
cytokines  interleukins  and other bioactive mediators. Neutrophils play a key role in innate
immunity against bacterial infections. The process of NETosis is a recently unraveled
sophisticated defense mechanism  consisting of the formation of neutrophil extracellular traps
that catch  immobilize  and remove pathogens from the body. Dysfunction of immunity is
indisputably conducive to the propensity for infections  particularly respiratory tract
infections  as the airways are the first line of defense against invading pathogens. Pathogens
can rapidly evolve and adapt to avoid detection by the immune system. The case in point is the
influenza virus. The articles report on the epidemiology  diagnostics  serology  complications
and the process of acquired immunity due to vaccination against influenza and influenza-like
infections in recent epidemic seasons. The book is a blend of medical research and practice. It
is intended for academic scientists  research scholars  clinicians  family doctors  and
healthcare professionals.

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