Tremor represents one of the most common movement disorders worldwide. It affects both sexes
and may occur at any age. In most cases tremor is disabling and causes social difficulties
resulting in poorer quality of life. Tremor is now recognized as a public health issue given
the aging of the population. Tremor is a complex phenomenon that has attracted the attention of
scientists from various disciplines. Tremor results from dynamic interactions between multiple
synaptically coupled neuronal systems and the biomechanical physical and electrical
properties of the external effectors. There have been major advances in our understanding of
tremor pathogenesis these last three decades thanks to new imaging techniques and genetic
discoveries. Moreover significant progress in computer technologies developments of reliable
and unobtrusive wearable sensors improvements in miniaturization and advances in signal
processing have opened new perspectives for the accurate characterization and daily monitoring
of tremor. New therapies are emerging. In this book we provide an overview of tremor from
pathogenesis to therapeutic aspects. We review the definitions the classification of the
varieties of tremor and the contribution of central versus peripheral mechanisms.
Neuroanatomical neurophysiological neurochemical and pharmacological topics related to
tremor are pointed out. Our goals are to explain the fundamental basis of tremor generation to
show the recent technological developments especially in instrumentation which are reshaping
research and clinical practice and to provide up-to-date information related to emerging
therapies. The integrative transdisciplinary approach has been used combining engineering and
physiological principles to diagnose monitor and treat tremor. Guidelines for evaluation of
tremor are explained. This book has been written for biomedical engineering students engineers
researchers medical students biologists neurologists and biomedical professionals of any
discipline looking for an updated and multidisciplinary overview of tremor. It can be used for
biomedical courses. Table of Contents: Introduction Anatomical Overview of the Central and
Peripheral Nervous System Physiology of the Nervous System Characterization of Tremor
Prinipal Disorders Associated with Tremor Quantification of Tremor Mechanisms of Tremor
Treatments
