The contributors to this publication are pathologists involved in specific tumour diagnostics
and molecular analysis. Various approaches described in the articles show the state-of-the-art
knowledge applied to studying heterogeneity in different types of tumours. Compared to a wide
range of available literature on intratumour heterogeneity in clinical research and diagnostics
the focus here is on practical methods for improving heterogeneity analysis of clinical
material. This is relevant because no standardized types of examinations currently exist. Thus
this publication serves as a basis for development of standards in tumour tissue sampling and
in reproducible molecular analysis and interpretation. This is an invaluable resource for
pathologists oncologists and molecular biologists. Other health professionals directly
involved in clinical treatment of tumours as well as in basic research will also benefit
greatly from this work.
