This Handbook takes the reader through the entire field of pediatric thrombosis and hemostasis
and has been updated since the 2nd edition with considerable new information and elements
missing in previous editions. The Handbook begins with an overview of the history of pediatric
thrombosis and hemostasis followed by a concise explanation of the complex pathophysiology of
thrombosis and hemostasis. It follows with chapters focused on disorders of hemostasis in
children from neonates to adolescents. Subsequent chapters are focused on thrombotic
complications in children together with workup and management of thrombophilias in children.
New chapters on bleeding in the adolescent girl and on management of children on mechanical
circulatory support (ECMO VAD) have been added. There is also a new chapter focused on
hemostatic and thrombotic challenges in children with vascular anomalies as pediatric
hemostasis and thrombosis clinicians are increasingly being asked to manage children with these
conditions. This updated Handbook is intended for health care professionals involved in the
assessment and care of children with inherited and acquired bleeding and thrombotic disorders
to inform and facilitate diagnostic treatment decisions. This includes general and specialist
pediatricians in particular intensivists neonatologists cardiologists cardiac surgeons
rheumatologists nephrologists and hematologists oncologists as well as medical trainees
residents fellows nurses nurse practitioners physician assistants and pharmacists.
