This comprehensive volume on the blood-gas barrier (BGB) among vertebrates covers its structure
and composition along with aspects of evolution bioengineering and morphometry. The book also
discusses the embryological development of the BGB including chronology of events and
molecular control in vertebrates modulation of the barrier function including cyclic
stretch-induced increases in alveolar epithelial permeability mechanisms of lung vascular
epithelial permeability transport mechanisms of the BGB including sodium transport channels
factors affecting trans-barrier traffic of fluids such as chronic elevation of pulmonary
microvascular pressure stress failure regulation and repair in acute lung injury chronic
lung disease and lung transportation.Ten authoritative chapters approach the blood-gas barrier
holistically from basic structure and development to pathology and treatment. Properties of
the BGB are discussed in the earlier chapters followed by prenatal and post-natal development
and mechanisms of the healthy BGB. The latter half of the book delves into the pathology of the
BGB analyzing common afflictions and exploring options for treatment including its
alterations during lung transplantation. Intuitively structured and comprehensive The
Vertebrate Blood-Gas Barrier in Health and Disease is ideal for researchers and clinicians
interested in pneumology and angiology.
