This book focuses primarily on the most efficient way to make an accurate FNA diagnosis of
metastatic tumors within the broad confines of cytopathology. The text provides a step-by-step
thought process during the diagnostic approach of the metastatic tumors using detailed
algorithms. Starting from the onsite immediate FNA sample assessment the book provides
strategy of specimen triage to facilitate further cytology evaluation based on the metastatic
patterns and morphologic patterns of the tumors. In the subsequent chapter the book provides
tips and traps of selecting markers and interpretation of immunoperoxidase flow cytometric
cytogenetic and molecular studies. The book includes the strategy of dealing with limited FNA
material and wisely use existing samples (cell block direct smear cytospin) for different
ancillary studies including molecular tests that have been used at MD Anderson. The author
highlights challenging issues to show the importance of using a multidisciplinary (clinical
radiologic cytologic and ancillary studies) approach. Extensive illustrations are provided.
Metastatic Neoplasms in Fine-Needle Aspiration Cytology will provide pathology residents
fellows practicing cytopathologists and cytotechnologists with a practical way to approach
metastatic malignancies in daily cytology practice as well as provide a vision of the future of
cytopathology.
