Thisbook constitutes the refereed proceedings of the 4th International Conferenceon
Bioinformatics and Biomedical Engineering IWBBIO 2016 held in Granada Spain in April
2016.The69 papers presented were carefully reviewed and selected from 286 submissions.The scope
of the conference spans the following areas: bioinformatics for healthcareand diseases
biomedical image analysis biomedical signal analysis computational systems for modeling
biological processes eHealth tools fornext generation sequencing data analysis assistive
technology for people withneuromotor disorders fundamentals of biological dynamics and
maximization ofthe information extraction from the experiments in the biological systems
highperformance computing in bioinformatics computational biology andcomputational chemistry
human behavior monitoring analysis and understanding pattern recognition and machine learning
in the -omics sciences and resourcesfor bioinformatics.