This book constitutes the proceedings of the 4th InternationalConference on Algorithms for
Computational Biology AlCoB 2017 held in Aveiro Portugal in June 2017. The 10 full papers
presented together with 2 invited papers were carefully reviewed and selected from 24
submissions. They are organized in the following topical sections: Graph Algorithms for
Computational Biology Phylogenetics and Sequence Analysis and Other Biological Processes.