Type IV secretion systems (T4SSs) are highly versatile membrane-associated transporter machines
used by Gram-negative and Gram-positive bacteria to deliver substrate molecules to a large
variety of target cells. This volume summarizes our current knowledge of the large variety and
structural diversity of T4SSs in pathogenic Escherichia Agrobacterium Legionella Coxiella
Bartonella Helicobacter Enterococcus and other species. Divided into 13 chapters contributed
by leading experts it presents findings that significantly enhance our understanding of how
various pathogens manipulate host cell functions to trigger bacterial uptake promote
intracellular growth suppress defense mechanisms and of how bacteria spread antibiotic
resistances thus facilitating bacterial colonization and disease development. The book is an
invaluable source of information for researchers and clinicians.
