This book is the first to provide balanced examination of both pediatric liver disease and
liver transplantation ¿ two topics that are inherently related given that most chronic liver
disorders eventually require organ replacement. The different forms of liver disease
encountered in the pediatric age group are first discussed in a series of disease-specific
chapters that have a reader-friendly uniform structure covering pathophysiology diagnostic
and treatment algorithms clinical cases and transition to adult care. Key topics in the field
of liver transplantation are then addressed. Examples include indications and contraindications
surgical techniques and complications immunosuppression in pediatric liver transplantation
acute and chronic rejection and allograft dysfunction and CMV and EBV infection in transplant
recipients long-term graft injury and tolerance. A section on pediatric hepatology across the
world includes chapters presenting the features and management of pediatric liver disease in
South-America Africa and Asia. A closing section considers what the future holds for pediatric
liver disease and its management including novel genetic testing cell therapy and gene
therapy. Pediatric Hepatology and Liver Transplantation will be of value for a range of
practitioners from residents making their first approach to pediatric liver disease through to
specialists working in transplantation centers.
