EAN: 9783731500452

MULTISCALE MODELING OF CARDIAC ELECTROPHYSIOLOG...

Multiscale modeling of cardiac electrophysiology helps to better understand the underlying
mechanisms of atrial fibrillation  acute cardiac ischemia and pharmacological treatment. For
this purpose  measurement data reflecting these conditions have to be integrated into models of
cardiac electrophysiology. Several methods for this model adaptation are introduced in this
thesis. The resulting effects are investigated in multiscale simulations ranging from the ion
channel up to the body surface. AbstractEnglisch = Multiscale modeling of cardiac
electrophysiology helps to better understand the underlying mechanisms of atrial fibrillation 
acute cardiac ischemia and pharmacological treatment. For this purpose  measurement data
reflecting these conditions have to be integrated into models of cardiac electrophysiology.
Several methods for this model adaptation are introduced in this thesis. The resulting effects
are investigated in multiscale simulations ranging from the ion channel up to the body surface.

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