This book presents a common principle of actions of long noncoding RNAs (lncRNAs) from points
of view at the atomic molecular and cellular levels. At the atomic level chemical studies of
ribonucleic acids explain the chemical behavior of lncRNAs. Structural biological analysis of
lncRNAs and its binding proteins also reveal the precise mechanisms of their actions. Molecular
biological approaches lead to insights into molecular mechanisms of these lncRNA actions. At
the cellular or individual level of analysis we grasp the biology and medicine of lncRNAs.
These three layers of approaches are thoroughly new and produce novel insights into functions
of lncRNAs in living cells. The book consists of five parts: 1) Bioinformatics and other
methodologies for lncRNAs 2) Atomic and molecular structures of lncRNAs 3) Molecular
functions of lncRNAs 4) Biological actions of lncRNAs and 5) Potential outcomes for clinical
medicine. These sections connect well and work synergistically. The book is for researchers
whose specialty is RNA biology and chemistry and also for advanced students at the graduate and
undergraduate levels. Readers can grasp the leading edge of lncRNA studies in a comprehensive
manner and are inspired to pursue their own particular interests.
