This book helps scientists clinicians and other interested individuals understand recent
clinical advances and challenges for the future. It covers many basic aspects of the
pathogenesis of chronic hepatitis C HCV infections in particular populations approaches to
therapy and prevention and control of HCV Infection. The book provides a succinct review of
the large amount of data generated by multiple groups over the past two decades that has
revealed the natural history of HCV infection. Similarly it summarizes current understanding
of the origins of HCV-associated hepatocellular carcinoma cirrhosis and hepatic fibrosis.
Extra-hepatic manifestation and metabolic disorders related to HCV infection are described. In
this volume these clinically important aspects of HCV infection are comprehensively described.
Highlights are description of newly developed direct- acting antivirals. The authors represent
a worldwide distribution of leaders in the field reflecting the global nature of HCV infection.
Based on recent data concerning the genetic- and geographical diversity of HCV and increased
global disease burden of HCV infection challenges for global control of HCV infections are
described.
