This book presents a comprehensive state-of-the-art review of the latest progresses in UHMWPE
biomaterials which has been critical for the performance and longevity of joint implants.
Oriented by clinical challenges to UHMWPE-based joint implants it introduces the processing
crosslinking structural manipulation oxidation mechanism stabilization drug delivery and
wear as well as clinical performance biomechanics and simulated studies of joint implant
based on UHMWPE with low wear which are aimed to tackle or minimize the adverse effect related
to wear and wear debris. These contributions provide fundamentals of chemistry and physics of
UHMWPEs to help understand the clinical performances of UHMWPE based joint implants.
Perspectives to next generation UHMWPE to meet the unmet challenges in clinical use are
included.
