EAN: 9780444626493

MEDICINAL CHEMISTRY OF ANTICANCER DRUGS - CARME...

Medicinal Chemistry of Anticancer Drugs  Second Edition  provides an updated treatment from the
point of view of medicinal chemistry and drug design  focusing on the mechanism of action of
antitumor drugs from the molecular level  and on the relationship between chemical structure
and chemical and biochemical reactivity of antitumor agents. Antitumor chemotherapy is a very
active field of research  and a huge amount of information on the topic is generated every
year. Cytotoxic chemotherapy is gradually being supplemented by a new generation of drugs that
recognize specific targets on the surface or inside cancer cells  and resistance to antitumor
drugs continues to be investigated. While these therapies are in their infancy  they hold
promise of more effective therapies with fewer side effects. Although many books are available
that deal with clinical aspects of cancer chemotherapy  this book provides a sorely needed
update from the point of view of medicinal chemistry and drug design.

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