EAN: 9781493926268

SYSTEMS BIOLOGY OF ALZHEIMERS DISEASE GEBUNDEN

Alzheimer's disease (AD) and many other neurodegenerative disorders are multifactorial in
nature  involving a combination of genomic  epigenomic  network dynamic and environmental
factors. A proper investigation requires new integrative Systems Biology approaches  at both
the experimental and computational level. The interplay of disease mechanisms and homeostatic
networks will underlie the time of onset and rate of progression of the disease.This book
addresses such an integrated approach to AD. It aims to present Systems Biology  including both
experimental and computational approaches  as a new strategy for the study of AD and other
multifactorial diseases  with the hope that the results will translate into more effective
diagnosis and treatment  as well as improved public health policies.Written for the highly
successful Methods in Molecular Biology series  practical and cutting-edge  Systems Biology of
Alzheimer's Disease is intended for post-graduate students  post-doctoral researchers and
experts in different fields with an interest in comprehensive Systems Biology strategies
applicable to AD and other complex multifactorial diseases (including other neurodegenerative
diseases and cancers). This book aims to complement other excellent volumes and monographs on
AD that cover fundamental  physiological or medical aspects of the disease.

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