Treatment of patients with intracranial gliomas especially high-grade neoplasms usually
requires postoperative adjuvant therapy. Significant progress in the understanding of tumor
biology technological advances in irradiation delivery and development of novel antitumor
drugs have led to an expansion of the therapeutic arsenal in neuro-oncology. This publication
provides a unique review of the various options for adjuvant therapy. Special emphasis is on
current evidence-based treatment standards and guidelines and on perspectives of further
improvement in long-term outcomes. Chapters review the histopathological and molecular features
of gliomas and describe basic principles and clinical results of fractionated radiotherapy
stereotactic radiosurgery brachytherapy use of radiosensitizers systemic chemotherapy and
antiangiogenic therapy. Particular attention is paid to treatment of pediatric patients and to
physical and psychological rehabilitation and supportive care at the end of life. This book and
its accompanying volumes are mainly directed at neuro-oncologists radiation oncologists and
other clinicians treating patients with brain tumors.
