EAN: 9783863598624

APPLIED MICROBIOLOGY MICROBIAL CATALYSIS OF R...

This work describes the domestication of Pseudomonas species to produce various aromatic
chemicals. The application of rational metabolic engineering strategies  including the deletion
and alteration of chromosomal elements and the overexpression of heterologous genes  resulted
in Pseudomonas taiwanensis strains that efficiently accumulate L-phenylalanine. Heterologous
expression of a plant gene then allowed high-yield synthesis of the aromatic building block
trans-cinnamate. The strains were further used as platform to produce several chemical
compounds of industrial interest  including styrene  pinosylvin  benzoate  catechol and cis
cis-muconate.

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