New Challenges for Cancer Systems Biomedicine Gebunden

The future of oncology seems to lie in Molecular Medicine (MM). MM is a new science based on three pillars. Two of them are evident in its very name and are well known: medical science and molecular biology. However there is a general unawareness that MM is firmly based on a third and equally important pillar: Systems Biomedicine. Currently this term denotes multilevel hierarchical models integrating key factors at the molecular cellular tissue through phenotype levels analyzed to reveal the global behavior of the biological process under consideration. It becomes increasingly evident that the tools to construct such complex models include not only bioinformatics and modern applied statistics as is unanimously agreed but also other interdisciplinary fields of science notably Mathematical Oncology Systems Biology and Theoretical Biophysics.