EAN: 9781848828216

BONE AND DEVELOPMENT GEBUNDEN

This is a sixth volume in a series of reviews  centered on a single major topic within the
field of osteopathy. The book is an appropriate mechanism for advancing knowledge in the field
to researchers  clinicians and others involved in the bone field. This work intends to look at
the role bone development within the field of pediatrics  covering all problematic aspects from
basic skeletal growth to tooth mineralization. To understand tissue development requires
combining embryological and histological knowledge with the increasing information becoming
available from molecular and genetic studies. Development is characterized by the expression of
genes  their subsequent silencing and the expression of other genes. Disease  especially
disease progression  is equally characterized by new gene expression that is then transmitted
to daughter cells  with the silencing of other genes. In both instances these sequences are the
result of the interaction between the genome and the epigenome  i.e. between a very stable set
of structures and rapidly changing environmental factors.

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