EAN: 9780124167216

BONE CANCER GEBUNDEN

Bone Cancer  Second Edition comprehensively investigates key discoveries in the field of bone
biology over the last five years that have led to the development of entirely new areas for
investigation  such as therapies which combine surgery and biological approaches. The Second
Edition expands on the original overview of bone cancer development (physiology and
pathophysiology)  with key chapters from the first edition  and offers numerous new chapters
describing the new concepts of bone cancer biology and therapy  for both primary bone tumors as
well as bone metastases. Each chapter has been written by internationally recognized
specialists on the bone cancer microenvironment  bone metastases  osteoclast biology in bone
cancer  proteomics  bone niche  circulating tumor cells  and clinical trials. Given the global
prevalence of breast and prostate cancers  knowledge of bone biology has become essential for
everyone within the medical and cancer research communities. Bone Cancer continues to offer the
only translational reference to cover all aspects of primary bone cancer and bone metastases -
from bench to bedside: development (cellular and molecular mechanisms)  genomic and proteomic
analyses  clinical analyses (histopathology  imaging  pain monitoring)  as well as new
therapeutic approaches and clinical trials for primary bone tumors and bone metastases.

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