EAN: 9783030247232

CANCER BIOMARKERS IN BODY FLUIDS - GABRIEL D DA...

The ability to measure and monitor cancer biomarkers in ¿body fluid biopsy¿ should greatly
impact oncologic practice. ¿Biomarkers in Proximal Fluids¿  the third of the ¿Cancer Biomarkers
in Body Fluids¿ series details cancer signatures in none or minimally circulating body fluids
including saliva  sputum  bronchoalveolar lavage fluid  exhaled breath condensate  nipple
aspirate fluid  gastric and pancreatic juice  stool  urine  and prostatic  peritoneal and
cerebrospinal fluid. These fluids are enriched with biomarkers  especially those emanating from
cells of the proximal tissue. Chapter 1 examines the global burden of cancer and the need for
regional efforts at primary prevention  early detection and patient care. Chapters 2-12 address
tissue-specific biomarkers in associated body fluids. The tumor interstitial fluid as a
microenvironment rich in cancer biomarkers is detailed in chapter 13  while chapter 14 looks at
the human body fluid microbiome and its evolving role in cancer. Commercially available assays
using proximal fluids are examined at the end of the respective chapters. This book complements
its predecessors and is equally useful to oncologists  cancer researchers  clinicians  medical
students  nurses  diagnostic laboratory and pharmaceutical industry personnel.

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