EAN: 9783319073194

OXIDATIVE STRESS AND INFLAMMATION IN NON-COMMUN...

Oxidative stress and inflammation underpin most diseases  their mechanisms are inextricably
linked. For example  chronic inflammation is associated with oxidation  anti-inflammatory
cascades are linked to decreased oxidation  increased oxidative stress triggers inflammation
and redox balance inhibits the inflammatory cellular response. Whether or not oxidative stress
and inflammation represent the causes or the consequences of cellular pathology  they
contribute significantly to the pathogenesis of non-communicable diseases. The incidence of
obesity and other related metabolic disturbances are rising  as are age-related diseases due to
progressively aging populations. Interrelations between the mechanisms of oxidative stress and
of inflammatory signaling and metabolism are  in the broad sense of energy transformation 
being increasingly recognized as part of the problem in non-communicable diseases. The book
Oxidative Stress and Inflammation in Non-communicable Diseases: Molecular Mechanisms and
Perspectives in Therapeutics is an update on the latest research on the molecular basis of
non-communicable diseases and the search for possible therapeutic alternatives. The authors of
this monograph are experts in their field and the book as a whole  provides an overview of the
biochemical alterations underlying diseases such as cardiovascular disease  cancer  obesity 
renal disease  neurological diseases and diabetes  emphasizing those aspects that they share in
common. We hope that this book will be useful for researchers in biomedicine and also for
physicians interested in finding the root causes of the disease  as well as for post-graduate
students in biochemistry  molecular biology  nutrition or medicine.

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