EAN: 9783319676500

BACTERIAL PATHOGENS AND THEIR VIRULENCE FACTORS...

Bacterial Pathogens and their Virulence Factors contains a detailed description of 32 major
bacterial pathogens that affect human health and their associated virulence determinants.
Chapter 1 gives an overview of the different types and classes of general virulence factors
involved in host cell adherence and invasion  dissemination within the host  host cell damage 
and evasion of host defense systems  as well as mechanisms by which these virulence factors are
regulated. Chapters 2 through 33 give concise descriptions of the disease states associated
with the 32 bacterial genera and their major pathogenic species  along with an in-depth
description of the individual virulence factors that have been found to be functionally
involved in pathogenicity. A detailed bibliography derived from primary literature and review
articles accompanies each of these chapters  allowing the reader to delve more deeply into
individual pathogens and their virulence determinants. Chapter 34 discusses the exciting
possibilities and initial successes of using detailed information on a pathogen¿s virulence
toolkit to design new therapeutics aimed at specific virulence traits.

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