EAN: 9783319946092

SPRINGERBRIEFS IN PHILOSOPHY EVALUATING EVIDE...

This book is open access under a CC BY license. This book is the first to develop explicit
methods for evaluating evidence of mechanisms in the field of medicine. It explains why it can
be important to make this evidence explicit  and describes how to take such evidence into
account in the evidence appraisal process. In addition  it develops procedures for seeking
evidence of mechanisms  for evaluating evidence of mechanisms  and for combining this
evaluation with evidence of association in order to yield an overall assessment of
effectiveness. Evidence-based medicine seeks to achieve improved health outcomes by making
evidence explicit and by developing explicit methods for evaluating it. To date  evidence-based
medicine has largely focused on evidence of association produced by clinical studies. As such 
it has tended to overlook evidence of pathophysiological mechanisms and evidence of the
mechanisms of action of interventions. The book offers a useful guide for all those whose work
involves evaluating evidence in the health sciences  including those who need to determine the
effectiveness of health interventions and those who need to ascertain the effects of
environmental exposures.

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