EAN: 9783318027297

AGING AND HEALTH - A SYSTEMS BIOLOGY PERSPECTIV...

Aging is a major risk factor for chronic diseases  which in turn can provide information about
the aging of a biological system. This publication serves as an introduction to systems biology
and its application to biological aging. Key pathways and processes that impinge on aging are
reviewed  and how they contribute to health and disease during aging is discussed. The
evolution of this situation is analyzed  and the consequences for the study of genetic effects
on aging are presented. Epigenetic programming of aging  as a continuation of development 
creates an interface between the genome and the environment. New research into the gut
microbiome describes how this interface may operate in practice with marked consequences for a
variety of disorders. This analysis is bolstered by a view of the aging organism as a whole 
with conclusions about the mechanisms underlying resilience of the organism to change  and is
expanded with a discussion of circadian rhythms in aging. Finally  the book presents an outlook
for the development of interventions to delay or to reverse the features of aging. The
publication is recommended to students  researchers as well as professionals dealing with
public health and public policy related to an aging society.

Aktuelle Preise zur EAN 9783318027297

Produktinformationen zur 9783318027297